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1- School of medicine, Guilan University of Medical Sciences, Rasht, Iran
2- School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Abstract:   (228 Views)
Introduction: Due to lack of a definitive treatment to improve humanchr(chr('39')39chr('39'))s cognitive disorders, researchers have focused on providing new approaches to partially improve or prevent the progression of memory and cognition disorders, in order to reduce the patientchr(chr('39')39chr('39'))s dependency on others. The enriched environment (EE) as a non-pharmacological treatment has drawn attention to improve the living conditions of the laboratory animals by increasing social, cognitive and physical stimuli. This review article discusses how the EE affects cognitive disorders and the mechanisms underlying it.
Methods: Present study was conducted with the aim of reviewing English articles in the field of EE and its effect on memory and cognitive disorders. In this article, the keywords Enriched environment and Memory and Cognitive impairment were searched in the titles and abstracts of articles published in reputable international scientific databases, and after several stages of removing duplicate and unrelated items, 69 articles were finally used.
Results: Enriched environment can improve memory and cognitive processes by creating a set of sensory, motor, social and cognitive stimuli. This improvement may be due to the EE different effects on the number of neurons, neurons morphology, myelination, synapses and neurotransmitters, neurotrophic factors and neuro-inflammation.
Conclusion: Considering the role of EE in improving molecular and functional disturbances of the central nervous system in diseases such as depression and stroke, and the potency to reduce the risk of humanchr(chr('39')39chr('39'))s dementia; It can be hoped that in the near future, the EE will be used in the treatment of humanchr(chr('39')39chr('39'))s neurodegenerative diseases as a suitable and pleasant non-pharmacological therapy.

Received: 2021/04/26 | Accepted: 2021/06/29

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