Volume 7, Issue 1 (Spring 2005)                   2005, 7(1): 10-17 | Back to browse issues page

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Kangarlou haghighi K, Zarindast M, Sadoughi M, Kalilzadeh A. The Effect of Cannabinoid System on Morphine-Induced State- Dependent Learning. Advances in Cognitive Science. 2005; 7 (1) :10-17
URL: http://icssjournal.ir/article-1-113-en.html
Abstract:   (448 Views)
Objective: In recent years cannabinoids and their use have attracted a great deal of attention. The aim of the present examination is to study the effect of the cannabinoid system and its interaction with the opioid system in state-dependent memory. 
Method: In this experimental study, the intracerebroventricular (ICV) administration of different doses of cannabinoid agonists and antagonists, and the subcutaneous administration of morphine was used in the passive avoidance task. 
Results: Cannabinoid agonists prevent the retrieval of memory by morphine. 
Conclusion: The improvement of retrieval memory by morphine treatment seems to be induced, at least in part, through the cannabinoid receptors.
Full-Text [PDF 382 kb]   (125 Downloads)    
Type of Study: Research | Subject: Special
Received: 2004/11/11 | Accepted: 2005/01/15 | Published: 2005/03/21

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